In the laboratory, it is possible to assess the risks during the handling of solid and liquid substances, during their transport, storage or processing, and proposals for preventive measures within the elimination of risks of technological procedures. The behavior of substances at temperatures below the ignition temperature is monitored by various methods, specially developed and standardized. Standardized methods include, for example, the Mackey test according to ASTM D3523-92 for the evaluation of oils and paints as well as the evaluation of substances with a tendency to spontaneous combustion according to regulations for the transport of dangerous goods by rail (RID) or road transport (ADR). Newly introduced methods include the method according to DIN 53436, which is used to evaluate the toxicity of combustion products of solid or liquid substances.